J. Steger, R. Micura*; ‘Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs’; Bioorg. Med. Chem. 2011, accepted.

A. Haller #, M. F. Soulière #, R. Micura*; ‘The dynamic nature of RNA as key to understanding riboswitch mechanisms’; Acc. Chem. Res. 2011, DOI: 10.1021/ar200035g. # these authors contributed equally

A. Haller, U. Rieder, M. Aigner, S. C. Blanchard*, R. Micura*; ‘Conformational capture of the SAM-II riboswitch’; Nat. Chem. Biol. 2011, 7, 393-400.
News&Views by Ming C. Hammond; ‘RNA folding: A tale of two riboswitches’; Nat. Chem. Biol. 2011, 7, 342-343.

H. Ramu, N. Vázquez-Laslop, D. Klepacki, Q. Dai, J. Piccirilli, R. Micura, A. S. Mankin*; ‘Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center’; Mol. Cell. 2011, 41, 321-330.
Preview by D. N. Wilson*; ‘Peptides in the Ribosomal Tunnel Talk Back’; Mol. Cell 2011, 41, 247-248.

M. Aigner, M. Hartl, K. Fauster, J. Steger, K. Bister, R. Micura*; ‘Chemical Synthesis of Site-Specifically 2′-Azido-Modified RNA and Potential Applications for Bioconjugation and RNA Interference’; Chembiochem 2011, 11, 47-51.

D. Graber, K. Trappl, J. Steger, A.-S. Geiermann, L. Rigger, H. Moroder, N. Polacek, R. Micura*; ‘Deoxyribozyme-based, semisynthetic access to stable peptidyl-tRNAs exemplified by tRNA(Val) carrying a macrolide antibiotic resistance peptide’; in Ribozymes (Ed. J. S. Hartig), Meth. Mol. Biol. 2011, in press.

J. Steger, D. Graber, H. Moroder, A.-S. Geiermann, M. Aigner, R. Micura*; ‘Efficient Access to Nonhydrolyzable Initiator tRNA Based on the Synthesis of 3′-Azido-3′-Deoxyadenosine RNA’; Angew. Chem. Int. Ed. Engl. 2010, 49, 7470-7472; Angew. Chem. 2010, 122, 7632-7634.

Y. Wang, J. Ludwig, C. Schuberth, M. Goldeck, M. Schlee, H. Li, S. Juranek, G. Sheng, R. Micura, T. Tuschl, G. Hartmann, D. J. Patel; ‘Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I’; Nat. Struct. Mol. Biol. 2010, 17, 781-787.

D. Graber, H. Moroder, J. Steger, K. Trappl, N. Polacek, R. Micura*; ‘Efficient semisynthesis of hydrolysis-resistant 3′-peptidyl-tRNA conjugates containing genuine tRNA modifications’; Nucl. Acids Res. 2010, 38, 6796-6802.

U. Rieder, C. Kreutz, R. Micura*; ‘Folding of a transcriptionally acting preQ1 riboswitch’; Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 10804-10809.

N. Clementi, A. Chirkova, B. Puffer, R. Micura, N. Polacek*; ‘Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation’; Nat. Chem. Biol. 2010, 6, 344-351.

A. Chirkova, M. Erlacher, R. Micura, N. Polacek*; ‘Chemically engineered ribosomes: A new frontier in synthetic biology’; Curr. Org. Chem. 2010, 14, 148-161.

A.-S. Geiermann, R. Micura*; ‘Chasing after antibiotic leads’; Chem. Biol. 2009, 16, 1024-1025 (Preview).

B. Puffer, C. Kreutz, U. Rieder, M.-O. Ebert, R. Konrat, R Micura*; ‘5-Fluoro pyrimidines: Labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy’;  Nucl. Acids Res. 2009, 37, 7728-7740.

K. De Mulder, D. Pfister, G. Kuales, B. Egger, W. Salvenmoser, M. Willems, J. Steger, K. Fauster, R. Micura, G. Borgonie, P. Ladurner*; ‘Stem cells are differentially regulated during development, regeneration and homeostasis in flatworms’; Dev. Biol. 2009, 334, 198-212.

U. Rieder, K. Lang, C. Kreutz, N. Polacek, R. Micura*; ‘Evidence for Pseudoknot Formation of Class I preQ1 Riboswitch Aptamers’; Chembiochem 2009, 10, 1141-1144.

H. Moroder #, J. Steger #, D. Graber, K. Fauster, K. Trappl, V. Marquez, N. Polacek, D. N. Wilson, R. Micura*; ‘Nonhydrolyzable RNA–Peptide Conjugates: A Powerful Advance in the Synthesis of Mimics for 3′-Peptidyl tRNA Termini’; Angew. Chem. Int. Ed. Engl. 2009, 48, 4056-4060; Angew. Chem. 2009, 121, 4116-4120. # these authors contributed equally

V. Olieric #, U. Rieder #, K. Lang, A. Serganov, C. Schulze-Briese, R. Micura, P. Dumas, E. Ennifar*; ‘A fast strategy for selenium derivatization directed to phasing of X-ray RNA structures’; RNA 2009, 15, 707-715. # these authors contributed equally

R. Rieder, C. Höbartner, R. Micura*; ‘Enzymatic ligation strategies for the preparation of purine riboswitches with site-specific chemical modifications’, in Riboswitches (Ed. A. Serganov), Meth. Mol. Biol. 2009, 540, 15-24.

D. Graber, H. Moroder, R. Micura*; ’19F NMR spectroscopy for the analysis of RNA secondary structure populations’; J. Am. Chem. Soc. 2008, 130, 17230–17231.

P. S. Pallan, C. Kreutz, S. Bosio, R. Micura*, Martin Egli*; ‘Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m22G:A pairs’, RNA 2008, 14, 2125-2135.

K. Lang, R. Micura*; ‘Preparation of site-specifically modified riboswitch domains as an example for enzymatic ligation of chemically synthesized RNA fragments’, Nature Protocols 2008, 3, 1457-1466.

K. Lang, M. Erlacher, D. N. Wilson, R. Micura*, N. Polacek*; ‘The role of 23S rRNA residue A2451 in ribosomal peptide bond synthesis revealed by atomic mutagenesis’; Chem. Biol. 2008, 15, 485-492.
Preview by M. Pech, K. H. Nierhaus*; ‘Ribosomal peptide-bond formation’; Chem. Biol. 2008, 15, 417-419.

R. Micura; contributions to ‘Nucleic Acids from A to Z – A Concise Encyclopedia‘; Ed.: Sabine Müller, Wiley-VCH, 2008.

F. Li, P. Pallan, M. Maier, K. Rajeev, S. Mathieu, C. Kreutz, Y. Fan, J. Sanghvi, R. Micura, E. Rozners, M. Manoharan, M. Egli*; ‘Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme’; Nucl. Acids Res. 2007, 35, 6424-6438.

K. Lang, R. Rieder, R. Micura*; ‘Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach’; Nucl. Acids Res. 2007, 35, 5370-5378.

M. Amort, B. Wotzel, K. Bakowska-Zywicka, M. D. Erlacher, R. Micura, and N. Polacek*; ‘An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination’; Nucl. Acids Res. 2007, 35, 5130-5140.

R. Rieder, K. Lang, D. Graber, R. Micura*; ‘Ligand-Induced Folding of the Adenosine Deaminase A-Riboswitch and Implications on Riboswitch Translational Control’; Chembiochem 2007, 8, 896 – 902.

R. Micura; ‘RNA – Struktur und Funktion’; Trendbericht, Nachrichten aus der Chemie 2007, 55, 279-284.

R. Micura, C. Höbartner, R. Rieder, C. Kreutz, B. Puffer, K. Lang, H. Moroder; ‘Preparation of 2′-Deoxy-2′-Methylseleno-Modified RNA’, Current Protocols in Nucleic Acid Chemistry (2006), Wiley, C1.15.1. – C1.15.34.

H. Moroder, C. Kreutz, K. Lang, A. Serganov*, and R. Micura*; ‘Synthesis, Oxidation Behavior, Crystallization and Structure of 2′-Methylseleno Guanosine Containing RNAs’; J. Am. Chem. Soc. 2006, 128, 9909-9918.

C. Kreutz, H. Kählig, R. Konrat*, R. Micura*; ‘A General Approach for the Identification of Site-Specific RNA Binders by 19F-NMR Spectroscopy – Proof of Concept’; Angew. Chem. 2006, 118, 3528-3532; Angew. Chem. Int. Ed. Engl. 2006, 45, 3450-3453.

M. D. Erlacher #, K. Lang #, B. Wotzel, R. Rieder, R. Micura*, N. Polacek*; ‘Efficient ribosomal peptidyl transfer critically relies on the presence of the ribose 2′-OH at A2451 of 23S rRNA’; J. Am. Chem. Soc. 2006, 128, 4453-4459. # these authors contributed equally

R. Micura*; ‘Programmable ligand-controlled riboregulators’; Angew. Chem. 2006, 118, 32-34; Angew. Chem. Int. Ed. Engl. 2006, 45, 30-31.

C. Kreutz, H. Kählig, R. Konrat*, R. Micura*, ‘Ribose 2′-F labeling: A simple tool for the characterization of RNA secondary structure equilibria by 19F-NMR spectroscopy’, J. Am. Chem. Soc. 2005, 127, 11558-11559.

C. Höbartner, R. Rieder, C. Kreutz, B. Puffer, K. Lang, A. Polonskaia, A. Serganov, R. Micura*, ‘Syntheses of RNAs with up to 100 nucleotides containing site-specific 2′-Se-methyl labels for use in X-ray crystallography’, J. Am. Chem. Soc. 2005, 127, 12035-12045.

M. D. Erlacher, K. Lang, N. Shankaran, B. Wotzel, A. Hüttenhofer, R. Micura, A. S. Mankin, N. Polacek*; ‘Chemical engineering of the peptidyl transferase center reveals an important role of the 2′-O-hydroxyl group of A2451’; Nucl. Acids Res. 2005, 33, 1618-1627.

A. Serganov, S. Keiper, L. Malinina, V. Tereshko, E. Skripkin, C. Hobartner, A. Polonskaia, A. T. Phan, R. Wombacher, R. Micura, Z. Dauter, A. Jaschke*, D. J. Patel*; ‘Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation’; Nat. Struct. Mol. Biol. 2005, 12, 218 – 224.

A. Serganov, Y. R. Yuan, O. Pikovskaya, A. Polonskaia, L. Malinina, A.T. Phan, C. Höbartner, R. Micura, R.R. Breaker, D.J. Patel*; ‘Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs’, Chem. Biol. 2004, 11, 1729-1741.

R. Micura*; ‘Genetic control by a natural metabolite-responsive ribozyme’; Angew. Chem. 2004, 116, 4797-4799; Angew. Chem. Int. Ed. Engl. 2004, 43, 4692-4694.

C. Hoebartner, H. Mittendorfer, K. Breuker, R. Micura*; ‘Triggering of RNA secondary structures by a functionalized nucleobase’; Angew. Chem. 2004, 116, 4012-4015; Angew. Chem. Int. Ed. Engl. 2004, 43, 3922-3925.

C. Hoebartner, R. Micura*; ‘The chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 snRNA stem-loop segment’; J. Am. Chem. Soc. 2004, 126, 1141-1149.

R. Micura*, C. Hoebartner; ‘Equilibria of RNA secondary structures‘, in Bioorganic Chemistry Highlights II: From Chemistry to Biology, Ed. C. Schmuck, H. Wennemers, WILEY-VCH, Weinheim, 2004, 3-16.

S. Pitsch, S. Wendeborn, R. Krishnamurthy*, A. Holzner, M. Minton, M. Bolli, C. Miculka, N. Windhab, R. Micura, M. Stanek, B. Jaun, A. Eschenmoser*; ‘The ß-D-Ribopyranosyl-(4′-2’)-Oligonucleotide System (‘Pyranosyl-RNA’): Synthesis and Resume of Base-Pairing Properties’; Helv. Chim. Acta 2003, 12, 4270-4363.

R. Micura*, and C. Hoebartner; ‘On RNA secondary structure rearrangements and equilibria of small RNAs’; ChemBioChem 2003, 4, 984-990.

C. Hoebartner, C. Kreutz, E. Flecker, E. Ottenschlaeger, W. Pils, K. Grubmayr, R. Micura*; ‘The synthesis of 2′-O-[(triisopropylsilyl)oxy]methyl (TOM) phosphoramidites of methylated ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for use in automated RNA solid-phase synthesis’; Monatshefte für Chemie – Chemical Monthly, 2003, 134, 851-873.

C. Hoebartner, R. Micura*; ‘Bistable secondary structures of small RNAs and their structural probing by comparative imino proton NMR spectroscopy’; J. Mol. Biol. 2003, 325, 421-431.

R. Micura*; ‘Small interfering RNAs and their chemical synthesis’; Angew. Chem. 2002, 114 (13), 2369-2373; Angew.Chem. Int. Ed. Engl. 2002, 41 (13), 2265-2269.

C. Hoebartner, M.-O. Ebert, B. Jaun, R. Micura*; ‘RNA two-state conformation equilibria and the effect of nucleobase methylation’; Angew. Chem. 2002, 114 (4), 619-623; Angew. Chem. Int. Ed. Engl. 2002, 41 (4), 605-609.

R. Micura*, W. Pils, C. Hoebartner, K. Grubmayr, M.-O. Ebert, B. Jaun; ‘Methylation of nucleobases in RNA oligonucleotides mediates hairpin-duplex conversion’; Nucleic Acids Res. 2001, 29, 3997-4005.

R. Micura*, W. Pils, K. Grubmayr, M.-O. Ebert, B. Jaun; ‘Bridged Cyclic Oligoribonucleotides – towards Models for Codon-Anticodon Pairing’; Nucleosides, Nucleotides, Nucleic Acids 2001, 20, 1287-1289.

R. Micura*, W. Pils, and K. Grubmayr; ‘Bridged Cyclic Oligoribonucleotides as Model Compounds for Codon-Anticodon Pairing’; Angew. Chem. 2000, 112, 956-958; Angew. Chem. Int. Ed. Engl. 2000, 39, 922-925.

W. Pils and R. Micura*, ‘Flexible non-nucleotide linkers as loop replacements in short duplex RNAs’; Nucleic Acids Res. 2000, 28, 1859-1863.

M.- O. Ebert, Bernhard Jaun* and W. Pils, R. Micura; ‘On RNA triplet interactions: NMR study of the short intramolecular duplex formed by (D)-r[GCAm1G-p-O(CH2CH2O)6-p-UGCC]’; Helv. Chem. Acta 2000, 83, 2338-2343.

R. Micura*; ‘Cyclic Oligoribonucleotides (RNA) by Solid Phase Synthesis’; Chemistry Eur. J. 1999, 5, 2077-2082.

R. Micura, R. Kudick and A. Eschenmoser*; ‘Opposite Orientation of Backbone Inclination in pyranosyl-RNA and homo-DNA Correlates with Opposite Directionality of Duplex Properties’; Angew. Chem. 1999, 111, 715-718; Angew. Chem. Int. Ed. Engl. 1999, 38, 680-683.

M. Bolli, R. Micura, S. Pitsch and A. Eschenmoser*; ‘Pyranosyl-RNA: Further Observations on Replication’; Helv. Chem. Acta 1997, 80, 1901-1951.

M. Bolli, R. Micura, and A. Eschenmoser*; ‘Pyranosyl-RNA: Chiroselective self-assembly of base sequences by ligative oligomerization of tetranucleotide-2′,3′-cyclophosphates (with a commentary concerning the origin of biomolecular homochirality)’; Chem.&Biol. 1997, 4, 309-320.

R. Micura, M. Bolli, N. Windhab and A. Eschenmoser*; ‘Pyranosyl-RNA Also Forms Hairpin Structures’, Angew. Chem. 1997, 109, 899-902; Angew. Chem. Int. Ed. Engl. 1997, 36, 870-873.

R. Micura* and K. Grubmayr; ‘The Enantiomers of Phycocyanobilin Dimethyl Ester: A Facile Approach via Semipreparative Enantioselective Chromatography of their Ring-D Methyl Imino Esters’; Enantiomer 1996, 1, 109-113.

H. Falk*, R. Micura, M. Stanek, and R. Wutka; ‘Structural Aspects of Native and Acid or Enzyme Degraded Amylopectins – a 13C NMR Study’, Starch/Stärke 1996; 48, 344-346.

H. Falk*, Q.-Q. Chen, and R. Micura; ‘On the Chemistry of Pyrrole Pigments, XCVII: Synthesis, Stereochemistry, and Solvatochromic Effects of a 1-(Dipyrrinon-9-yl)-3-(dipyrrinon-9-ylidene)-1-propene’; Monatsh. 1996, 127, 77-83.

R. Micura and K. Grubmayr*; ‘A Phycocyanobilin Seryliminoester as a New Model for the Chromophore-Protein Interaction in Phytochrome’; Angew. Chem. 1995, 107, 1896-1898; Angew. Chem. Int. Ed. Engl. 1995, 34, 1733-1735.

Q.-Q. Chen, H. Falk*, and R. Micura; ‘On the Chemistry of Pyrrole Pigments, XCII: Syntheses of 1,2-Bis-pyrrolylethanes’; Monatsh. 1995, 126, 473-479.

R. Micura and K. Grubmayr*; ‘Long-wavelength absorbing derivatives of phycocyanobilin: new structural aspects on phytochrome’; Bioorg. Med. Chem. Lett. 1994, 4, 2517-2522.