Publications

 

2017
 
N. Vusurovic #, R. B. Altman #, D. S. Terry, R. Micura*, S. C. Blanchard*; 'Pseudoknot formation seeds the twister ribozyme cleavage reaction coordinate'; J. Am. Chem. Soc. 2017, 139, 8186-8193. # these authors contributed equally
 
H. Glasner, C. Riml, R. Micura, K. Breuker*; 'Label-free, direct localization and quantitation of the RNA nucleobase methylations m6A, m5C, m3U, and m5U by top-down mass spectrometry'; Nucl. Acids Res. 2017, online.
 
J. Gebetsberger, R. Micura*; 'Unwinding the twister ribozyme: From structure to mechanism'; WIREs RNA 2017, 8:e1402.
 
L. Jud, R. Micura*; 'An unconventional acid-labile nucleobase protection concept for guanosine phosphoramidites in RNA solid-phase synthesis'; Chem. Eur. J. 2017, 23, 3406–3413.
 
T. Amort, D. Rieder, A. Wille, D. Khokhlova-Cubberley, C. Riml, L. Trixl, X.-Y. Jia, R. Micura, A. Lusser*; 'Distinct 5-methylcytosine profiles in poly(A)RNA from mouse embryonic stem cells and the brain'; Genome Biology, 2017, 18, 1.
 
S. Neuner, C. Kreutz*, R. Micura*; 'The synthesis of 15N(7)-Hoogsteen face-labeled adenosine phosphoramidite for solid-phase RNA synthesis'; Monatshefte für Chemie - Chemical Monthly, 2017, 148, 149-155. Special Issue "Organic chemistry – Austrian Chemical Society (GÖCH) work group"
2016
 
M. Frener, R. Micura*; 'Conformational rearrangements of individual nucleotides during RNA-ligand binding are rate-differentiated'; J. Am. Chem. Soc. 2016, 138, 3627-3630.
 
E. Mairhofer #, E. Fuchs #, R. Micura*; 'Facile synthesis of 3-deazaadenosine phosphoramidite for RNA solid-phase synthesis'; Beilstein J. Org. Chem. 2016, 12, 2556-2562. # these authors contributed equally
 
A. Ren #, N. Vusurovic #, J. Gebetsberger, P. Gao, M. Juen, C. Kreutz, R. Micura,* D.J. Patel*; 'Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage'; Nat. Chem. Biol. 2016, 12, 702-708. # these authors contributed equally
 
S. Melnikov, J. Mailliot, L. Rigger, S. Neuner, B.-S. Shin, G. Yusupova, T. E. Dever,* R. Micura*, M. Yusupov*; 'Molecular insights into protein synthesis with proline residues'; EMBO Reports 2016, 17, 1776-1784.
 
S. Sothiselvam, S. Neuner, L. Rigger, D. Klepacki, R. Micura, N. Vázquez-Laslop,* A. S. Mankin*; 'The ribosome corrupted by macrolide antibiotics discriminates against specific substrates based on their charge and size'; Cell Reports 2016, 16, 1789-1799.
 
C. Riml, R. Micura*; 'Synthesis of 5-hydroxymethylcytidine and 5-hydroxymethyluridine-modified RNA'; Synthesis 2016, 48, 1108-1116.
 
S. Melnikov, J. Mailliot, B.-S. Shin, L. Rigger, G. Yusupova, R. Micura*, T. E. Dever,* M. Yusupov*; 'Crystal structure of hypusine-containing translation fachtor eIF5A bound to a rotated eukaryotic ribosome'; J. Mol. Biol. 2016, 428, 3570-3576.
 
S. Flür, R. Micura*; 'Chemical synthesis of RNA with site-specific methylphosphonate modifications'; Methods 2016, 107, 79-88.
2015
 
M. Kosutic #, S. Neuner #, A. Ren, S. Flür, C. Wunderlich, E. Mairhofer, N. Vusurovic, J. Seikowski, K. Breuker, C. Höbartner, D.J. Patel,* C. Kreutz,* R. Micura*; 'A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class'; Angew. Chem. Int. Ed. 2015, 54, 15128-15233. # these authors contributed equally
 
S. Neuner #, T. Santner #, C. Kreutz, R. Micura*; 'The "speedy" synthesis of atom-specific 15N imino/amido-labeled RNA'; Chem. Eur. J. 2015, 21, 11634-11643. # these authors contributed equally.
 
L. Jud #, M. Kosutic #, V. Schwarz, M. Hartl, C. Kreutz, K. Bister, R. Micura*; 'Expanding the scope of 2'-SCF3 modified RNA'; Chem. Eur. J. 2015, 21, 10400-10407. # these authors contributed equally.
 
M. Koch #, S. Flür #, C. Kreutz, R. Micura*, N. Polacek*; 'The role of a ribosomal RNA phosphate oxygen during the EF-G-triggered GTP hydrolysis'; Proc. Nat. Acad. Sci. 2015, 112, E6256–E6259. # these authors contributed equally.
 
C. Riml, H. Glasner, M. T. Rodgers, R. Micura, K. Breuker*; 'On the mechanism of RNA phosphodiester backbone cleavage in the absence of solvent'; Nucl. Acids Res. 2015, 43, 5171-5181.
 
T. Moschen, C. H. Wunderlich, R. Spitzer, J. Levic, R. Micura, M. Tollinger*, C. Kreutz*; 'Ligand-Detected Relaxation Dispersion NMR Spectroscopy: Dynamics of preQ1–RNA Binding'; Angew. Chem. Int. Ed. 2015, 570-573.
 
A.-S. Geiermann, R. Micura; 'Native chemical Ligation of hydrolysis-resistant 3'-NH-cystein-modified RNA'; Curr. Protoc. Nucl. Acid Chem. 2015, Wiley, 62:4.64.1-4.64.36.
2014
 
A. Ren #, M. Kosutic #, K. R. Rajashankar, M. Frener, T. Santner, E. Westhof, R. Micura*, D. J. Patel*; 'In-line alignment and Mg2+ coordination at the cleavage site of the env22 twister ribozyme'; Nat. Commun. 2014, 5: 5534. # these authors contributed equally; Pascal Legault, Faculty of 1000 Structural Biology.
 
S. Neuner, R. Micura*; 'Synthesis of aminoacetylated N6,N6-dimethyladenosine solid support for efficient access to hydrolysis-resistant 3'-charged tRNA mimics'; Bioorg. Med. Chem. 2014, 22, 6989-6995.
 
F. Spenkuch, G. Hinze, S. Kellner, C. Kreutz, R. Micura, T. Basché, M. Helm*; 'Dye label interference with RNA modification reveals 5-fluorouridine as non-covalent inhibitor'; Nucl. Acids Res. 2014, 42, 12735-12745.
 
J. Levic, R. Micura*; 'Syntheses of 15N-labeled pre-queuosine base derivatives'; Beilstein J. Org. Chem. 2014, 10, 1914-1918.
 
M. Kosutic #, L. Jud #, C. Da Veiga, M. Frener, K. Fauster, C. Kreutz, E. Ennifar*, R. Micura*; 'Surprising base pairing and structural properties of 2'-Trifluoromethylthio-Modified RNA'; J. Am. Chem. Soc. 2014, 136, 6656-6663. # these authors contributed equally
 
T. Santner, M. Hartl, K. Bister, R. Micura*; 'Efficient access to 3'-terminal azide-modified RNA for inverse Click-labeling patterns'; Bioconj. Chem. 2014, 25, 188-195.
 
M. F. Soulière*, R. Micura*; 'Use of SHAPE to select 2AP substitution sites for RNA-ligand interactions and dynamics studies'; in Therapeutic applications of ribozymes and riboswitches (Eds. D. Lafontaine, A. Dubé), Meth. Mol. Biol. 2014, 1103, 227-239.
2013
 
M. F. Soulière, R. B. Altman, V. Schwarz, A. Haller, S. C. Blanchard*, R. Micura*; 'Tuning a riboswitch response through structural extension of a pseudoknot'; Proc. Nat. Acad. Sci. 2013, 110, E3256-E3264.
  R. Micura*; 'RNA biophysics: A three-state balancing act'; Nature 2013, 499, 289-290 (News&Views).
 
L. Rigger, R. L. Schmidt, K. M. Holman, M. Simonovic*, R. Micura*; 'The synthesis of methylated, phosphorylated, and phosphonated 3'-aminoacyl-tRNASec mimics'; Chem. Eur. J. 2013, 19, 15872-15878. (Front cover)
 
M. Duval, A Korepanov, O. Fuchsbauer, P. Fechter, A. Haller, A. Fabbretti, L. Choulier, R. Micura, B. Klaholz, P. Romby*, M. Springer, S. Marzi*; 'Escherichia coli ribosomal protein S1 unfolds structured mRNA onto the ribosome for active translation initiation'; PLoS Biology 2013, 11(12), e1001731.
 
G. Bec, B. Meyer, M.-A. Gerard, J. Steger, K. Fauster, P. Wolff, D. Bernouf, R. Micura, P. Dumas, E. Ennifar*; 'Thermodynamics of HIV-1 reverse transcriptase in action elucidates the mechanism of action of non-nucleoside inhibitors'; J. Am. Chem. Soc. 2013, 135, 9743–9752.
 
R. Micura*, C. Kreutz*, K. Breuker*; 'A personal perspective on chemistry-driven RNA research'; Biopolymers 2013, 99, 1114-1123.
 
T. Amort, M. F. Soulière, A. Wille, X.-Y. Jia, H. Fiegl, H. Wörle, R. Micura, A. Lusser*; 'Long non-coding RNAs as targets for cytosine methylation'; RNA Biology 2013, 10, 1002-1008.
 
A. Haller, R. B. Altman, M. Soulière, S. C. Blanchard*, R. Micura*; 'Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution'; Proc. Nat. Acad. Sci. 2013, 110, 4188-4193.
 
M. F. Soulière, A. Haller, T. Santner, R. Micura*; 'New Insights into Gene Regulation - High Resolution Structures of Cobalamin Riboswitches'; Angew. Chem. Int. Ed. 2013, 52, 1874-1877; Angew. Chem. 2013, 125, 1924-1927.
2012
 
K. Fauster, C. Kreutz, R. Micura*; '2'-SCF3 uridine - A novel powerful label for probing RNA structure and function by 19F-NMR spectroscopy'; Angew. Chem. Int. Ed. 2012, 51, 13080-13084; Angew. Chem. 2012, 124,13257-13261.
 
V. Siegmund, T. Santner, R. Micura, A. Marx*; 'Screening mutant libraries of T7 RNA polymerase for candidates with increased acceptance of 2'-modified nucleotides'; Chem. Comm. 2012, 48, 9870-9872.
 
T. Santner #, U. Rieder #, C. Kreutz*, R. Micura*; 'Pseudoknot preorganization of the preQ1 class I riboswitch'; J. Am. Chem. Soc. 2012, 134, 11928-11931. # these authors contributed equally
 
A.-S. Geiermann, R. Micura*; 'Selective desulfurization significantly expands sequence variety of 3’-peptidyl-tRNA mimics obtained by native chemical ligation'; Chembiochem 2012, 12,1742-1745.
 
T. Santner, V. Siegmund, A. Marx, R. Micura*; The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates; Bioorg. Med. Chem. 2012, 20, 2416-2418. (Front cover)
 
K. Fauster, M. Hartl, T. Santner, M. Aigner, C. Kreutz, K. Bister*, E. Ennifar*, R. Micura*; 2-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling; ACS Chem. Biol. 2012, 7, 581-589. (Front cover)
 
R. Micura; book review on 'Metal Ions in Life Sciences, Vol. 9., Structural and Catalytic Roles of Metal Ions in RNA', A. Sigel, H. Sigel, R.K.O. Sigel (Eds.) RSC Publishing (2011); Coord. Chem. Rev. 2012, 256, 370.
 
D. Graber, K. Trappl, J. Steger, A.-S. Geiermann, L. Rigger, H. Moroder, N. Polacek, R. Micura*; 'Deoxyribozyme-based, semisynthetic access to stable peptidyl-tRNAs exemplified by tRNA(Val) carrying a macrolide antibiotic resistance peptide'; in Ribozymes (Ed. J. S. Hartig), Meth. Mol. Biol. 2012, 848, 201-213.
2011
 
A.-S. Geiermann, N. Polacek, R. Micura*; 'Native chemical ligation of hydrolysis-resistant 3’-peptidyl-tRNA mimics'; J. Am. Chem. Soc. 2011, 133, 19068-19071.
 
M. Soulière, A. Haller, R. Rieder, R. Micura*; 'A powerful approach for the selection of 2-aminopurine substitution sites to investigate RNA folding'; J. Am. Chem. Soc. 2011, 133, 16161-16167.
 
V. Siegmund, T. Santner, R. Micura*, A. Marx*; 'Enzymatic synthesis of 2'-methylseleno-modified RNA'; Chem. Sci. 2011, 2, 2224-2231.
 
J. Steger, R. Micura*; 'Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs'; Bioorg. Med. Chem. 2011, 19, 5167-5174.
 
A. Haller #, M. F. Soulière #, R. Micura*; 'The dynamic nature of RNA as key to understanding riboswitch mechanisms'; Acc. Chem. Res. 2011, 44, 1339-1348. # these authors contributed equally
 
A. Haller, U. Rieder, M. Aigner, S. C. Blanchard*, R. Micura*; 'Conformational capture of the SAM-II riboswitch'; Nat. Chem. Biol. 2011, 7, 393-400.
News&Views by Ming C. Hammond; 'RNA folding: A tale of two riboswitches'; Nat. Chem. Biol. 2011, 7, 342-343.
 
H. Ramu, N. Vázquez-Laslop, D. Klepacki, Q. Dai, J. Piccirilli, R. Micura, A. S. Mankin*; 'Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center'; Mol. Cell. 2011, 41, 321-330.
Preview by D. N. Wilson*; 'Peptides in the Ribosomal Tunnel Talk Back'; Mol. Cell 2011, 41, 247-248.
 
M. Aigner, M. Hartl, K. Fauster, J. Steger, K. Bister, R. Micura*; 'Chemical Synthesis of Site-Specifically 2'-Azido-Modified RNA and Potential Applications for Bioconjugation and RNA Interference'; Chembiochem 2011, 11, 47-51.
2010
 
J. Steger, D. Graber, H. Moroder, A.-S. Geiermann, M. Aigner, R. Micura*; 'Efficient Access to Nonhydrolyzable Initiator tRNA Based on the Synthesis of 3′-Azido-3′-Deoxyadenosine RNA'; Angew. Chem. Int. Ed. Engl. 2010, 49, 7470-7472; Angew. Chem. 2010, 122, 7632-7634.
 
Y. Wang, J. Ludwig, C. Schuberth, M. Goldeck, M. Schlee, H. Li, S. Juranek, G. Sheng, R. Micura, T. Tuschl, G. Hartmann, D. J. Patel; 'Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I'; Nat. Struct. Mol. Biol. 2010, 17, 781-787.
 
D. Graber, H. Moroder, J. Steger, K. Trappl, N. Polacek, R. Micura*; 'Efficient semisynthesis of hydrolysis-resistant 3'-peptidyl-tRNA conjugates containing genuine tRNA modifications'; Nucl. Acids Res. 2010, 38, 6796-6802.
 
U. Rieder, C. Kreutz, R. Micura*; 'Folding of a transcriptionally acting preQ1 riboswitch'; Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 10804-10809.
 
N. Clementi, A. Chirkova, B. Puffer, R. Micura, N. Polacek*; 'Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation'; Nat. Chem. Biol. 2010, 6, 344-351.
 
A. Chirkova, M. Erlacher, R. Micura, N. Polacek*; 'Chemically engineered ribosomes: A new frontier in synthetic biology'; Curr. Org. Chem. 2010, 14, 148-161.
2009
 
A.-S. Geiermann, R. Micura*; 'Chasing after antibiotic leads'; Chem. Biol. 2009, 16, 1024-1025 (Preview).
 
B. Puffer, C. Kreutz, U. Rieder, M.-O. Ebert, R. Konrat, R Micura*; '5-Fluoro pyrimidines: Labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy';  Nucl. Acids Res. 2009, 37, 7728-7740.
 
K. De Mulder, D. Pfister, G. Kuales, B. Egger, W. Salvenmoser, M. Willems, J. Steger, K. Fauster, R. Micura, G. Borgonie, P. Ladurner*; 'Stem cells are differentially regulated during development, regeneration and homeostasis in flatworms'; Dev. Biol. 2009, 334, 198-212.
 
U. Rieder, K. Lang, C. Kreutz, N. Polacek, R. Micura*; 'Evidence for Pseudoknot Formation of Class I preQ1 Riboswitch Aptamers'; Chembiochem 2009, 10, 1141-1144.
 
H. Moroder #, J. Steger #, D. Graber, K. Fauster, K. Trappl, V. Marquez, N. Polacek, D. N. Wilson, R. Micura*; 'Nonhydrolyzable RNA–Peptide Conjugates: A Powerful Advance in the Synthesis of Mimics for 3'-Peptidyl tRNA Termini'; Angew. Chem. Int. Ed. Engl. 2009, 48, 4056-4060; Angew. Chem. 2009, 121, 4116-4120. # these authors contributed equally
 
V. Olieric #, U. Rieder #, K. Lang, A. Serganov, C. Schulze-Briese, R. Micura, P. Dumas, E. Ennifar*; 'A fast strategy for selenium derivatization directed to phasing of X-ray RNA structures'; RNA 2009, 15, 707-715. # these authors contributed equally
 
R. Rieder, C. Höbartner, R. Micura*; 'Enzymatic ligation strategies for the preparation of purine riboswitches with site-specific chemical modifications', in Riboswitches (Ed. A. Serganov), Meth. Mol. Biol. 2009, 540, 15-24.
2008
 
D. Graber, H. Moroder, R. Micura*; '19F NMR spectroscopy for the analysis of RNA secondary structure populations'; J. Am. Chem. Soc. 2008, 130, 17230–17231.
 
P. S. Pallan, C. Kreutz, S. Bosio, R. Micura*, Martin Egli*; 'Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m22G:A pairs', RNA 2008, 14, 2125-2135.
 
K. Lang, R. Micura*; 'Preparation of site-specifically modified riboswitch domains as an example for enzymatic ligation of chemically synthesized RNA fragments', Nature Protocols 2008, 3, 1457-1466.
 
K. Lang, M. Erlacher, D. N. Wilson, R. Micura*, N. Polacek*; 'The role of 23S rRNA residue A2451 in ribosomal peptide bond synthesis revealed by atomic mutagenesis'; Chem. Biol. 2008, 15, 485-492.
Preview by M. Pech, K. H. Nierhaus*; 'Ribosomal peptide-bond formation'; Chem. Biol. 2008, 15, 417-419.
 
S. Freisz, K. Lang, R. Micura, P. Dumas, E. Ennifar*; 'Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site'; Angew. Chem. 2008, 120, 4178-4181; Angew. Chem. Int. Ed. Engl. 2008, 47, 4110-4113.
 
B. Puffer, H. Moroder, M. Aigner, R. Micura*; '2'-Methylseleno modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach'; Nucl. Acids Res. 2008, 36, 970-983.
 
C. Kreutz, R. Micura*; 'Investigations on fluorine-labeled ribonucleic acids by 19F NMR spectroscopy'; Modified Nucleotides in Biochemistry, Biotechnology and Medicine; Ed.: P. Herdewijn, Wiley-VCH, 2008, 3-22.
 
R. Micura; contributions to 'Nucleic Acids from A to Z – A Concise Encyclopedia'; Ed.: Sabine Müller, Wiley-VCH, 2008.
2007
 
F. Li, P. Pallan, M. Maier, K. Rajeev, S. Mathieu, C. Kreutz, Y. Fan, J. Sanghvi, R. Micura, E. Rozners, M. Manoharan, M. Egli*; 'Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme'; Nucl. Acids Res. 2007, 35, 6424-6438.
 
K. Lang, R. Rieder, R. Micura*; 'Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach'; Nucl. Acids Res. 2007, 35, 5370-5378.
 
M. Amort, B. Wotzel, K. Bakowska-Zywicka, M. D. Erlacher, R. Micura, and N. Polacek*; 'An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination'; Nucl. Acids Res. 2007, 35, 5130-5140.
 
R. Rieder, K. Lang, D. Graber, R. Micura*; 'Ligand-Induced Folding of the Adenosine Deaminase A-Riboswitch and Implications on Riboswitch Translational Control'; Chembiochem 2007, 8, 896 - 902.
 
R. Micura; 'RNA Struktur und Funktion'; Trendbericht, Nachrichten aus der Chemie 2007, 55, 279-284.
2006
 
R. Micura, C. Höbartner, R. Rieder, C. Kreutz, B. Puffer, K. Lang, H. Moroder; 'Preparation of 2'-Deoxy-2'-Methylseleno-Modified RNA', Curr. Protoc. Nucl. Acid Chem. 2006, Wiley, C1.15.1. - C1.15.34.
 
H. Moroder, C. Kreutz, K. Lang, A. Serganov*, and R. Micura*; 'Synthesis, Oxidation Behavior, Crystallization and Structure of 2'-Methylseleno Guanosine Containing RNAs'; J. Am. Chem. Soc. 2006, 128, 9909-9918.
 
C. Kreutz, H. Kählig, R. Konrat*, R. Micura*; 'A General Approach for the Identification of Site-Specific RNA Binders by 19F-NMR Spectroscopy - Proof of Concept'; Angew. Chem. 2006, 118, 3528-3532; Angew. Chem. Int. Ed. Engl. 2006, 45, 3450-3453.
 
M. D. Erlacher #, K. Lang #, B. Wotzel, R. Rieder, R. Micura*, N. Polacek*; 'Efficient ribosomal peptidyl transfer critically relies on the presence of the ribose 2'-OH at A2451 of 23S rRNA'; J. Am. Chem. Soc. 2006, 128, 4453-4459. # these authors contributed equally
 
R. Micura*; 'Programmable ligand-controlled riboregulators'; Angew. Chem. 2006, 118, 32-34; Angew. Chem. Int. Ed. Engl. 2006, 45, 30-31.
2005
 
C. Kreutz, H. Kählig, R. Konrat*, R. Micura*, 'Ribose 2'-F labeling: A simple tool for the characterization of RNA secondary structure equilibria by 19F-NMR spectroscopy', J. Am. Chem. Soc. 2005, 127, 11558-11559.
 
C. Höbartner, R. Rieder, C. Kreutz, B. Puffer, K. Lang, A. Polonskaia, A. Serganov, R. Micura*, 'Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-Se-methyl labels for use in X-ray crystallography', J. Am. Chem. Soc. 2005, 127, 12035-12045.
 
M. D. Erlacher, K. Lang, N. Shankaran, B. Wotzel, A. Hüttenhofer, R. Micura, A. S. Mankin, N. Polacek*; 'Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-O-hydroxyl group of A2451'; Nucl. Acids Res. 2005, 33, 1618-1627.
 
A. Serganov, S. Keiper, L. Malinina, V. Tereshko, E. Skripkin, C. Hobartner, A. Polonskaia, A. T. Phan, R. Wombacher, R. Micura, Z. Dauter, A. Jaschke*, D. J. Patel*; 'Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation'; Nat. Struct. Mol. Biol. 2005, 12, 218 - 224.
2004
 
A. Serganov, Y. R. Yuan, O. Pikovskaya, A. Polonskaia, L. Malinina, A.T. Phan, C. Höbartner, R. Micura, R.R. Breaker, D.J. Patel*; 'Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs', Chem. Biol. 2004, 11, 1729-1741.
 
R. Micura*; 'Genetic control by a natural metabolite-responsive ribozyme'; Angew. Chem. 2004, 116, 4797-4799; Angew. Chem. Int. Ed. Engl. 2004, 43, 4692-4694.
 
C. Hoebartner, H. Mittendorfer, K. Breuker, R. Micura*; 'Triggering of RNA secondary structures by a functionalized nucleobase'; Angew. Chem. 2004, 116, 4012-4015; Angew. Chem. Int. Ed. Engl. 2004, 43, 3922-3925.
 
C. Hoebartner, R. Micura*; 'The chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 snRNA stem-loop segment'; J. Am. Chem. Soc. 2004, 126, 1141-1149.
 
R. Micura*, C. Hoebartner; 'Equilibria of RNA secondary structures', in Bioorganic Chemistry Highlights II: From Chemistry to Biology, Ed. C. Schmuck, H. Wennemers, WILEY-VCH, Weinheim, 2004, 3-16.
2003
 
S. Pitsch, S. Wendeborn, R. Krishnamurthy*, A. Holzner, M. Minton, M. Bolli, C. Miculka, N. Windhab, R. Micura, M. Stanek, B. Jaun, A. Eschenmoser*; 'The ß-D-Ribopyranosyl-(4'-2')-Oligonucleotide System ('Pyranosyl-RNA'): Synthesis and Resume of Base-Pairing Properties'; Helv. Chim. Acta 2003, 12, 4270-4363.
 
R. Micura*, and C. Hoebartner; 'On RNA secondary structure rearrangements and equilibria of small RNAs'; ChemBioChem 2003, 4, 984-990.
 
C. Hoebartner, C. Kreutz, E. Flecker, E. Ottenschlaeger, W. Pils, K. Grubmayr, R. Micura*; 'The synthesis of 2'-O-[(triisopropylsilyl)oxy]methyl (TOM) phosphoramidites of methylated ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for use in automated RNA solid-phase synthesis'; Monatshefte für Chemie - Chemical Monthly, 2003, 134, 851-873.
 
C. Hoebartner, R. Micura*; 'Bistable secondary structures of small RNAs and their structural probing by comparative imino proton NMR spectroscopy'; J. Mol. Biol. 2003, 325, 421-431.
2002
 
R. Micura*; 'Small interfering RNAs and their chemical synthesis'; Angew. Chem. 2002, 114 (13), 2369-2373; Angew.Chem. Int. Ed. Engl. 2002, 41 (13), 2265-2269.
 
C. Hoebartner, M.-O. Ebert, B. Jaun, R. Micura*; 'RNA two-state conformation equilibria and the effect of nucleobase methylation'; Angew. Chem. 2002, 114 (4), 619-623; Angew. Chem. Int. Ed. Engl. 2002, 41 (4), 605-609.
2001
 
R. Micura*, W. Pils, C. Hoebartner, K. Grubmayr, M.-O. Ebert, B. Jaun; 'Methylation of nucleobases in RNA oligonucleotides mediates hairpin-duplex conversion'; Nucleic Acids Res. 2001, 29, 3997-4005.
 
R. Micura*, W. Pils, K. Grubmayr, M.-O. Ebert, B. Jaun; 'Bridged Cyclic Oligoribonucleotides - towards Models for Codon-Anticodon Pairing'; Nucleosides, Nucleotides, Nucleic Acids 2001, 20, 1287-1289.
2000
 
R. Micura*, W. Pils, and K. Grubmayr; 'Bridged Cyclic Oligoribonucleotides as Model Compounds for Codon-Anticodon Pairing'; Angew. Chem. 2000, 112, 956-958; Angew. Chem. Int. Ed. Engl. 2000, 39, 922-925.
 
W. Pils and R. Micura*, 'Flexible non-nucleotide linkers as loop replacements in short duplex RNAs'; Nucleic Acids Res. 2000, 28, 1859-1863.
 
M.- O. Ebert, Bernhard Jaun* and W. Pils, R. Micura; 'On RNA triplet interactions: NMR study of the short intramolecular duplex formed by (D)-r[GCAm1G-p-O(CH2CH2O)6-p-UGCC]'; Helv. Chem. Acta 2000, 83, 2338-2343.
1999
 
R. Micura*; 'Cyclic Oligoribonucleotides (RNA) by Solid Phase Synthesis'; Chemistry Eur. J. 1999, 5, 2077-2082.
 
R. Micura, R. Kudick and A. Eschenmoser*; 'Opposite Orientation of Backbone Inclination in pyranosyl-RNA and homo-DNA Correlates with Opposite Directionality of Duplex Properties'; Angew. Chem. 1999, 111, 715-718; Angew. Chem. Int. Ed. Engl. 1999, 38, 680-683.
1997
 
M. Bolli, R. Micura, S. Pitsch and A. Eschenmoser*; 'Pyranosyl-RNA: Further Observations on Replication'; Helv. Chem. Acta 1997, 80, 1901-1951.
 
M. Bolli, R. Micura, and A. Eschenmoser*; 'Pyranosyl-RNA: Chiroselective self-assembly of base sequences by ligative oligomerization of tetranucleotide-2',3'-cyclophosphates (with a commentary concerning the origin of biomolecular homochirality)'; Chem.&Biol. 1997, 4, 309-320.
 
R. Micura, M. Bolli, N. Windhab and A. Eschenmoser*; 'Pyranosyl-RNA Also Forms Hairpin Structures', Angew. Chem. 1997, 109, 899-902; Angew. Chem. Int. Ed. Engl. 1997, 36, 870-873.
1996
 
R. Micura* and K. Grubmayr; 'The Enantiomers of Phycocyanobilin Dimethyl Ester: A Facile Approach via Semipreparative Enantioselective Chromatography of their Ring-D Methyl Imino Esters'; Enantiomer 1996, 1, 109-113.
 
H. Falk*, R. Micura, M. Stanek, and R. Wutka; 'Structural Aspects of Native and Acid or Enzyme Degraded Amylopectins - a 13C NMR Study', Starch/Stärke 1996; 48, 344-346.
 
H. Falk*, Q.-Q. Chen, and R. Micura; 'On the Chemistry of Pyrrole Pigments, XCVII: Synthesis, Stereochemistry, and Solvatochromic Effects of a 1-(Dipyrrinon-9-yl)-3-(dipyrrinon-9-ylidene)-1-propene'; Monatsh. 1996, 127, 77-83.
1995
 
R. Micura and K. Grubmayr*; 'A Phycocyanobilin Seryliminoester as a New Model for the Chromophore-Protein Interaction in Phytochrome'; Angew. Chem. 1995, 107, 1896-1898; Angew. Chem. Int. Ed. Engl. 1995, 34, 1733-1735.
 
Q.-Q. Chen, H. Falk*, and R. Micura; 'On the Chemistry of Pyrrole Pigments, XCII: Syntheses of 1,2-Bis-pyrrolylethanes'; Monatsh. 1995, 126, 473-479.
1994
 
R. Micura and K. Grubmayr*; 'Long-wavelength absorbing derivatives of phycocyanobilin: new structural aspects on phytochrome'; Bioorg. Med. Chem. Lett. 1994, 4, 2517-2522.